ImmunologybioRxivPreprint
Mincle-GSDMD-mediated release of IL-1β containing small extracellular vesicles contributes to ethanol-induced liver injury
DOI 10.1101/2022.11.30.518545
Author
M. R. McMullen
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2021-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 36 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
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Recent·Most cited
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Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.
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This study shows that GsdmD in myeloid cells promotes lung cancer metastasis in mice by enhancing inflammasome activity and IL-1β release.
DOI 10.1016/j.isci.2023.106076 - BiochemistrybioRxiv
Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice
R. N. Helsley, T. Miyata, A. Kadam…·J. M. Brown
This study shows elevated trimethylamine (TMA) in alcohol-associated hepatitis patients and demonstrates that inhibiting gut microbial TMA production protects mice from ethanol-induced liver injury.
DOI 10.7554/elife.76554