Author

K. C. Ngan

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

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B. B. Liau· 1 shared C. Lee· 1 shared E. M. Garcia· 1 shared J. G. Doench· 1 shared N. Z. Lue· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperBiochemistry

B. B. Liau

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1 paper

Recent·Most cited

BiochemistrybioRxivApr 12, 2022

Base editor scanning charts the DNMT3A activity landscape

N. Z. Lue, E. M. Garcia, K. C. Ngan…·B. B. Liau

The paper uses base editing and a DNA methylation reporter to scan DNMT3A mutations, identifying functional perturbations and revealing a noncanonical DNA affinity role for the PWWP domain.

DOI 10.1038/s41589-022-01167-4

DNA methylationexperimental assay

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