Perturbational single-cell profiling of patient tumors defines lineage- and context-specific programs of innate immune resistance
C. Perry, A. Frey, Y. Fei, J. Wang, P. Costa, H. N. Amin, S. Ghadermarzi, D. Levine, W. Tong, A. Koda, M. Mackie, M. He, Y. Nie, K. Clulo, F. Ouerghi, , J.J. Ishizuka
The paper uses patient tumor samples to identify lineage- and context-specific mechanisms of innate immune resistance through perturbational single-cell RNA sequencing.
bioRxiv · Dec 12, 2025 · PreprintCancer Biology