ImmunologybioRxivPreprint
The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin
M. Damo, C. Cui, I. William…·N. S. Joshi
The paper shows that PD-1+ CD8 T cells in healthy skin remain tolerant to self-antigens and prevent tissue damage through PD-L1 upregulation on myeloid cells.
DOI 10.1101/2021.07.09.451765