PhysiologybioRxivPreprint
Cell-autonomous and non-cell-autonomous effects of arginase-II on cardiac aging
D. M. Potenza, X. Cheng, G. AJALBERT…·X.-F. Ming
This study identifies non-cell-autonomous and cell-autonomous roles of arginase-II in cardiac aging, showing its impact on inflammation, fibrosis, and ischemic injury through macrophage-derived IL-1β and fibroblast mtROS.