Author

K. DeMeester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Cravatt· 2 shared B. Melillo· 2 shared D. Ogasawara· 2 shared E. Njomen· 2 shared H. Li· 2 shared S. J. Won· 2 shared S. Schreiber· 2 shared A. Saghatelian· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

B. Cravatt

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2 papers

Recent·Most cited

Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes

D. Ogasawara, D. Konrad, Z. Y. Tan, K. Carey, J. Luo, S. J. Won, H. Li, T. Carter, K. DeMeester, E. Njomen, S. Schreiber, R. Xavier, B. Melillo, B. Cravatt

The paper introduces photo-stereoprobes for expanding the ligandable proteome and demonstrates their use in discovering bioactive small molecules.

bioRxiv · Feb 27, 2024Biochemistry

Proteomic discovery of chemical probes that perturb protein complexes in human cells

M. Lazear, J. Remsberg, M. Jaeger, K. Rothamel, H.-l. Her, K. DeMeester, E. Njomen, S. Hogg, J. Rahman, L. Whitby, S. J. Won, M. Schafroth, D. Ogasawara, M. Yokoyama, G. Lindsey, , B. Cravatt

This study develops a proteomic strategy to identify chemical probes that perturb protein complexes in human cells by analyzing electrophilic compounds' effects on protein interactions.

bioRxiv · Dec 12, 2022Biochemistry