Mix-and-extrude: high-viscosity sample injection towards time-resolved protein crystallography
M. Vakili, H. Han, C. Schmidt, A. Wrona, M. Kloos, I. de Diego, K. Dorner, T. Geng, C. Kim, F. Koua, D. Melo, M. Rappas, A. Round, E. Round, M. Sikorski, , J. Schulz
This paper introduces a mix-and-extrude method for time-resolved protein crystallography using 3D printed microchannels to study ligand-induced reactions in viscous media.
bioRxiv · Nov 23, 2022Biochemistry