Author

K. E. Lake

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

D. G. McFadden· 1 shared J. K. De Brabander· 1 shared J. Kim· 1 shared J. M. Povedano Selfa· 1 shared R. Rallabandi· 1 shared V. Li· 1 shared X. Bai· 1 shared Y. Xie· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

D. G. McFadden

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1 paper

Recent·Most cited

Cancer BiologybioRxivNov 19, 2021

TK216 targets microtubules in Ewing sarcoma cells

J. M. Povedano Selfa, V. Li, K. E. Lake…·D. G. McFadden

This study identifies TK216 as a microtubule destabilizing agent that causes cytotoxicity in Ewing sarcoma cells, explaining its synergy with vincristine and suggesting reevaluation of its clinical trials.

DOI 10.1016/j.chembiol.2022.06.002

humanexperimental assay

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