Author

K. E. Lopez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

A. N. Rizo· 2 shared A. C. Thwin· 1 shared A. Diallo· 1 shared A. F. Brilot· 1 shared A. Fossati· 1 shared A. L. Lucius· 1 shared A. M. Smith· 1 shared A. Mancino· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

A. N. Rizo

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Author profile →

2 papers

Recent·Most cited

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

M. Gupta, C. M. Azumaya, M. Moritz, S. Pourmal, A. Diallo, G. E. Merz, G. M. Jang, M. Bouhaddou, A. Fossati, A. F. Brilot, D. Diwanji, E. Hernandez, N. Herrera, H. T. Kratochvil, V. L. Lam, , K. I Pawar

The paper uses cryo-EM and AlphaFold2 to determine the structure of SARS-CoV-2 Nsp2, revealing its zinc-binding site and potential interactions with host proteins.

bioRxiv · May 10, 2021 · PreprintBiophysics

Conformational Plasticity of the ClpAP AAA+ Protease Couples Protein Unfolding and Proteolysis

K. E. Lopez, A. N. Rizo, E. Tse, J. Lin, N. W. Scull, A. C. Thwin, A. L. Lucius, J. Shorter, D. R. Southworth

This study determines high-resolution structures of E. coli ClpAP complex in substrate-bound states to elucidate the mechanism of protein unfolding and proteolysis coupling.

bioRxiv · Oct 29, 2019Biophysics