Structural Insights into Regulation of Insulin Expression Involving i-Motif DNA Structures in the Insulin-Linked Polymorphic Region.
D. Guneri, E. Alexandrou, K. El Omari…·Z. A. E. Waller
This study investigates how sequence variants in the insulin-linked polymorphic region form i-motif and G-quadruplex DNA structures, which regulate insulin gene expression.