Oligomerisation mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptor
C. Vela-Rodriguez, C. Yang, H. I. Alanen, R. Eki, T. A. Abbas, M. M. Maksimainen, T. Glumoff, R. Duman, A. Wagner, B. M. Paschal, L. Lehtiö
This study identifies the D2 domain of DTX3L as critical for forming oligomeric complexes that enable the DTX3L-PARP9 complex to read mono-ADP-ribosylated androgen receptor.
bioRxiv · Nov 29, 2023 · PreprintBiochemistry