Cell BiologybioRxiv
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
H. Liu, C.-H. Zhang, N. Ammanamanchi…·B. Kuhn
This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.
DOI 10.1126/scitranslmed.aaw6419