Author

D. Kostka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Bais· 1 shared A. K. Holloway· 1 shared A. S. Bais· 1 shared B. Ganapathy· 1 shared B. J. Aronow· 1 shared B. Kuhn· 1 shared C. Guillermier· 1 shared C. K. Kuo· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Bais

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

iPSC modeling shows uncompensated mitochondrial mediated oxidative stress underlies early heart failure in hypoplastic left heart syndrome

X. Xu, K. Jin, A. S. Bais, W. Zhu, H. Yagi, T. N. Feinstein, P. Nguyen, J. Criscione, X. Liu, G. Beutner, K. B. Karunakaran, P. Adams, C. K. Kuo, D. Kostka, G. S. Pryhuber, , C. W. Lo

This study uses iPSC-derived cardiomyocytes to show that mitochondrial oxidative stress and ER stress underlie early heart failure in HLHS patients.

bioRxiv · May 9, 2021 · PreprintCell Biology

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

H. Liu, C.-H. Zhang, N. Ammanamanchi, S. Suresh, C. Lewarchik, K. Rao, G. M. Uys, L. Han, M. Abrial, D. Yimlamai, B. Ganapathy, C. Guillermier, N. Chen, M. Khaladkar, J. Spaethling, , B. Kuhn

This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.

bioRxiv · Oct 4, 2019Cell Biology

Developmental loci harbor clusters of accelerated regions that evolved independently in ape lineages

D. Kostka, A. K. Holloway, K. Pollard

The paper identifies lineage-specific accelerated regions in ape genomes, showing similar patterns of accelerated evolution in developmental regulatory elements across multiple apes.

bioRxiv · Nov 28, 2017Evolutionary Biology