Author

K. J. Chalut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

E. K. Paluch· 3 shared C. Labouesse· 2 shared K. Franze· 2 shared A. Chaigne· 1 shared A. Dimitracopoulos· 1 shared A. Hallou· 1 shared A. Winkel· 1 shared B. D. Simons· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCell Biology

E. K. Paluch

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A biomechanical switch regulates the transition towards homeostasis in esophageal epithelium

J. McGinn, A. Hallou, S. Han, K. Krizic, S. Ulyanchenko, R. Iglesias-Bartolome, F. J. England, C. Verstreken, K. J. Chalut, K. B. Jensen, B. D. Simons, M. P. Alcolea

The paper investigates how mechanical changes in the mouse esophagus regulate the transition to homeostasis by identifying a committed progenitor population through single-cell RNA sequencing and organ stretching experiments.

bioRxiv · Feb 3, 2021Cell Biology

Mouse embryonic stem cells switch migratory behaviour during early differentiation

I. M. Aspalter, W. Poenisch, K. J. Chalut, E. K. Paluch

The paper shows that naive mouse embryonic stem cells switch from amoeboid-like to mesenchymal-like migration as they exit the pluripotent state.

bioRxiv · Dec 7, 2020 · PreprintCell Biology

Cortical cell stiffness is independent of substrate mechanics

J. Rheinlaender, A. Dimitracopoulos, B. Wallmeyer, N. M. Kronenberg, K. J. Chalut, M. C. Gather, T. Betz, G. T. Charras, K. Franze

The paper shows that cortical cell stiffness is not affected by substrate mechanics after correcting for substrate deformation during AFM measurements.

Nature Materials · May 25, 2020Peer-reviewedBiophysics

Membrane tension mediated mechanotransduction drives fate choice in embryonic stem cells

H. De Belly, P. H. Jones, E. K. Paluch, K. J. Chalut

This study shows that membrane tension changes regulate endocytosis and fate transitions in embryonic stem cells.

bioRxiv · Oct 9, 2019Cell Biology

Abscission couples cell division to embryonic stem cell fate

A. Chaigne, C. Labouesse, M. Agnew, E. Hannezo, K. J. Chalut, E. K. Paluch

The paper shows that abscission couples cell division to exit from naive pluripotency in mouse embryonic stem cells.

bioRxiv · Oct 8, 2019Cell Biology

StemBond hydrogels optimise the mechanical microenvironment for embryonic stem cells

C. Labouesse, C. C. Agley, B. X. Tan, M. Hofer, A. Winkel, G. G. Stirparo, H. T. Stuart, C. M. Verstreken, W. Mansfield, P. Bertone, K. Franze, J. C. R. Silva, K. J. Chalut

This study develops StemBond hydrogels that independently control substrate stiffness and ECM tethering, showing they enhance ES cell self-renewal and reprogramming efficiency.

bioRxiv · Sep 13, 2019 · PreprintCell Biology