Author

K. K. Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

E. S. O'Brien· 2 shared A. I. Basbaum· 1 shared A. Koehl· 1 shared A. Makriyannis· 1 shared B. K. Kobilka· 1 shared B. K. Shoichet· 1 shared C. Habrian· 1 shared C. Iliopoulos-Tsoutsouvas· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

E. S. O'Brien

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Author profile →

2 papers

Recent·Most cited

Step-wise activation of a Family C GPCR

K. K. Kumar, H. Wang, C. Habrian, N. R. Latorraca, J. Xu, E. S. O'Brien, C. Zhang, E. Montabana, A. Koehl, S. Marqusee, E. Y. Isacoff, B. K. Kobilka

The paper proposes a step-wise activation model for metabotropic glutamate receptor subtype 5, supported by structural and fluorescence imaging data of different activation states.

bioRxiv · Aug 29, 2023 · PreprintBiophysics

Large library docking for cannabinoid-1 receptor agonists with reduced side effects

T. A. Tummino, C. Iliopoulos-Tsoutsouvas, J. M. Braz, E. S. O'Brien, R. M. Stein, V. Craik, N. K. Tran, S. Ganapathy, F. Liu, Y. Shiimura, F. Tong, T. C. Ho, D. S. Radchenko, Y. S. Moroz, S. R. Rosado, , B. K. Shoichet

The paper identifies a new cannabinoid-1 receptor agonist with reduced side effects through large library docking and experimental validation.

bioRxiv · Feb 27, 2023 · PreprintPharmacology & Toxicology