Author

K. Karstoft

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. B. Klein· 2 shared A. M. Fritzen· 2 shared C. Clemmensen· 2 shared J. Lund· 2 shared M. Kleinert· 2 shared R. J. Seeley· 2 shared T. S. Nicolaisen· 2 shared B. Finan· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

A. B. Klein

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Author profile →

2 papers

Recent·Most cited

The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

A. B. Klein, T. S. Nicolaisen, K. Johann, A. M. Fritzen, C. V. Mathiesen, C. Gil, N. S. Pilmark, K. Karstoft, M. B. Blond, J. S. Quist, R. J. Seeley, K. Faerch, J. Lund, M. Kleinert, C. Clemmensen

This study shows metformin increases GDF15 but does not rely on the GDF15-GFRAL pathway for its weight-lowering effects in mice.

bioRxiv · Feb 16, 2022Physiology

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

A. B. Klein, T. S. Nicolaisen, N. Ortenblad, K. D. Gejl, R. Jensen, A. M. Fritzen, E. L. Larsen, K. Karstoft, H. E. Poulsen, T. Morville, R. E. Sahl, J. W. Helge, J. Lund, S. Falk, M. Lyngbaek, , C. Clemmensen

The paper shows that exercise increases circulating GDF15 levels, but this physiological increase does not suppress appetite or exercise motivation like pharmacological GDF15.

bioRxiv · Oct 23, 2020Physiology