Cell BiologybioRxiv
A limited number of double-strand DNA breaks are sufficient to delay cell cycle progression.
J. van den Berg, A. G. Manjon, K. Kielbassa…·R. H. Medema
The paper shows that a single DNA double-strand break can trigger a checkpoint response that delays cell cycle progression, and its abrogation leads to micronucleated daughter cells.
DOI 10.1093/nar/gky786