MicrobiologybioRxiv
Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain
T. J. C. Tan, M. Yuan, K. Kuzelka…·N. C. Wu
The paper identifies two public IGHV3-53/3-66 clonotypes with distinct CDR H3 motifs and shows Y58F mutation enhances binding affinity to SARS-CoV-2 RBD.
DOI 10.1038/s41467-021-24123-7