BioengineeringbioRxiv
Rapid generation of potent antibodies by autonomous hypermutation in yeast
A. Wellner, C. McMahon, M. S. A. Gilman…·C. C. Liu
This paper introduces AHEAD, a yeast-based system for rapid antibody generation through autonomous hypermutation, achieving high-affinity antibodies against SARS-CoV-2 and other targets in just 2 weeks.
DOI 10.1038/s41589-021-00832-4