BiophysicsbioRxiv
Energetics and Conformational Pathways of Functional Rotation in the Multidrug Transporter AcrB
Y. Matsunaga, T. Yamane, T. Terada…·A. Kidera
This study calculates the minimum free energy pathway of functional rotation in AcrB, linking it to proton translocation and drug transport at the atomic level.
DOI 10.7554/elife.31715