Author

K. Mossman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Banerjee· 5 shared S. Mubareka· 4 shared J. A. Hirota· 3 shared L. Yip· 3 shared M. A. Ostrowski· 3 shared M. S. Miller· 3 shared P. Budylowski· 3 shared A. C. Doxey· 2 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

A. Banerjee

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Author profile →

5 papers

Recent·Most cited

Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

J. Liu, P. Budylowski, R. Samson, B. D. Griffin, G. Babuadze, B. Rathod, K. Colwill, J. A. Abioye, J. A. Schwartz, R. Law, L. Yip, S. K. Ahn, S. Chau, M. Naghibosadat, Y. Arita, , M. A. Ostrowski

This paper evaluates a SARS-CoV-2 mRNA vaccine, PTX-COVID19-B, showing it is safe, effective, and induces strong immune responses in mice and hamsters, with ongoing human clinical trials.

bioRxiv · May 11, 2021Immunology

Human coronaviruses disassemble processing bodies

M. Kleer, R. P. Mulloy, C.-A. Robinson, D. Evseev, M. P. Bui-Marinos, E. L. Castle, A. Banerjee, S. Mubareka, K. Mossman, J. A. Corcoran

This study shows SARS-CoV-2 and related coronaviruses induce processing body disassembly, with SARS-CoV-2's N protein uniquely causing this effect, leading to increased proinflammatory cytokine production.

bioRxiv · Nov 8, 2020Microbiology

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

A. Banerjee, N. El-Sayes, P. Budylowski, D. Richard, H. Maan, J. Aguiar, K. Baid, M. R. D'Agostino, J. C. Ang, B. J.- M. Tremblay, S. Afkhami, M. Karimzadeh, A. T. Irving, L. Yip, M. A. Ostrowski, , K. Mossman

This study shows SARS-CoV-2 infection induces a mild type I IFN response in vitro and in moderate COVID-19 cases, and cannot inhibit exogenous IFN induction.

bioRxiv · Jun 18, 2020Immunology

Isolation, sequence, infectivity and replication kinetics of SARS-CoV-2

A. Banerjee, J. A. Nasir, P. Budylowski, L. Yip, P. Aftanas, N. Christie, A. Ghalami, K. Baid, A. R. Raphenya, J. A. Hirota, M. S. Miller, A. J. McGeer, M. A. Ostrowski, R. A. Kozak, A. G. McArthur, , S. Mubareka

The paper isolates SARS-CoV-2 from two patients, sequences the virus, and tests its infectivity in human immune cells, finding that PBMCs are not permissive to infection.

bioRxiv · Apr 11, 2020 · PreprintMicrobiology

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

J. A. Aguiar, B. J.-M. Tremblay, M. J. Mansfield, O. Woody, B. Lobb, A. Banerjee, A. Chandiramohan, N. Tiessen, A. Dvorkin-Gheva, S. Revill, M. S. Miller, C. Carlsten, L. Organ, C. Joseph, A. John, , J. A. Hirota

The paper examines gene expression and protein localization of potential SARS-CoV-2 receptors in human airway epithelial cells and lung tissue, finding low ACE2 expression and confirming other candidate receptors.

bioRxiv · Apr 7, 2020Immunology