Author

S. Afkhami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Kang· 2 shared A. Zganiacz· 2 shared G. Ye· 2 shared J. Bavananthasivam· 2 shared J. C. Ang· 2 shared M. Jeyanathan· 2 shared M. R. D'Agostino· 2 shared M. S. Miller· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Kang

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Author profile →

3 papers

Recent·Most cited

Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung

A. Kang, G. Ye, R. Singh, S. Afkhami, J. Bavananthasivam, X. Luo, M. Vaseghi-Shanjani, A. Zganiacz, M. Jeyanathan, Z. Xing

This study shows subcutaneous BCG vaccination enhances innate protection against Streptococcus pneumoniae by accelerating neutrophilia in the lung, independent of monocyte training.

bioRxiv · Sep 29, 2022Immunology

Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

S. Afkhami, M. R. D'Agostino, A. Zhang, H. D. Stacey, A. Marzok, A. Kang, R. Singh, J. Bavananthasivam, G. Ye, X. Luo, F. Wang, J. C. Ang, A. Zganiacz, U. Sankar, N. Kazhdan, , Z. Xing

This study evaluates a multivalent Ad-vectored vaccine delivered via respiratory mucosal route, showing robust protection against SARS-CoV-2 and variants in mice.

bioRxiv · Jul 16, 2021Immunology

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

A. Banerjee, N. El-Sayes, P. Budylowski, D. Richard, H. Maan, J. Aguiar, K. Baid, M. R. D'Agostino, J. C. Ang, B. J.- M. Tremblay, S. Afkhami, M. Karimzadeh, A. T. Irving, L. Yip, M. A. Ostrowski, , K. Mossman

This study shows SARS-CoV-2 infection induces a mild type I IFN response in vitro and in moderate COVID-19 cases, and cannot inhibit exogenous IFN induction.

bioRxiv · Jun 18, 2020Immunology