Cell BiologybioRxiv
Pirfenidone attenuates lung fibrotic fibroblast-mediated fibrotic responses to transforming growth factor-β1
J. Jin, S. Togo, K. Kadoya…·K. Takahashi
This study shows pirfenidone reduces fibrotic responses in lung fibroblasts by inhibiting CTHRC1, suggesting it as a potential therapeutic target for lung fibrosis.
DOI 10.1186/s12931-019-1093-z