Cell BiologybioRxiv
Mechanisms of Kinesin-1 activation by Ensconsin/MAP7 in vivo
M. Metivier, B. Monroy, E. Gallaud…·R. Giet
This study identifies the Kinesin-1 activation mechanism by Ensconsin/MAP7, showing that the KBD domain binds and stimulates Kinesin-1 binding to Mts, with full-length Ensconsin enabling direct activation on microtubules.
DOI 10.1242/dev.171579