PathologybioRxiv
Hyperactivation of YAP/TAZ drives alterations in mesangial cells through stabilization of N-MYC in diabetic nephropathy
S. Choi, S. H. Suh, H. Bae…·G. Y. Koh
This study shows that YAP/TAZ hyperactivation in mesangial cells drives diabetic nephropathy by stabilizing N-Myc, leading to cellular impairments and disease progression.