Author

K. Pendyala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

P. Purkayastha· 2 shared T. P. Lele· 2 shared A. S. Saxena· 1 shared B. Yu· 1 shared C. F. Baer· 1 shared D. E. Conway· 1 shared H. Hakimjavadi· 1 shared J. I. Cabe· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

P. Purkayastha

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2 papers

Recent·Most cited

Rho activation drives luminal collapse and eversion in epithelial acini

V. Narayanan, P. Purkayastha, B. Yu, K. Pendyala, S. Chukkapalli, J. I. Cabe, R. B. Dickinson, D. E. Conway, T. P. Lele

This study shows that RhoA activation causes apical-out eversion in epithelial acini by altering mechanical homeostasis and surface tension differences.

bioRxiv · Jul 6, 2022Biophysics

Reverse plasticity underlies rapid evolution by clonal selection within populations of fibroblastspropagated on a novel soft substrate

P. Purkayastha, K. Pendyala, A. S. Saxena, H. Hakimjavadi, S. Chamala, P. D. Dixit, C. F. Baer, T. P. Lele

This study shows that reverse plasticity drives rapid evolution in fibroblasts adapted to soft substrates through genetic changes, not phenotypic plasticity alone.

bioRxiv · Apr 26, 2020 · PreprintEvolutionary Biology