R. B. Dickinson

This paper establishes a geometric principle explaining nuclear shapes based on surface area and volume constraints, showing that nuclear shape is determined by geometry rather than cytoskeletal forces.

This study shows that RhoA activation causes apical-out eversion in epithelial acini by altering mechanical homeostasis and surface tension differences.

The paper shows lamin A/C enables nuclear deformation through fibrous environments by acting like surface tension, allowing nuclei to bypass obstacles without rupturing.