Author

K. Prins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Organism:rat· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. Kazmirczak· 4 shared J. B. Mendelson· 3 shared S. Prisco· 3 shared L. M. Hartweck· 2 shared M. Blake· 2 shared N. T. Vogel· 2 shared B. Kremer· 1 shared B. S. Jhun· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

F. Kazmirczak

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Junctophilin-2 Regulates Mitochondrial Metabolism

S. Prisco, L. M. Hartweck, F. Kazmirczak, J. B. Mendelson, S. L. Deng, S. K. Lahiri, X. Wehrens, K. Prins

This study shows JPH2 regulates mitochondrial metabolism in the right ventricle, with gene therapy improving RV function in a rat model of RVD.

Circulation · Aug 20, 2024Peer-reviewedPhysiology

Ketone Bodies in Right Ventricular Failure: A Unique Therapeutic Opportunity

M. Blake, P. Puchalska, F. Kazmirczak, T. Thenappan, P. Crawford, K. Prins

This study investigates the effects of ketone bodies in right ventricular failure, showing improved RV function and reduced inflammation in a rat model.

bioRxiv · Apr 26, 2023Biochemistry

Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension

F. Kazmirczak, N. T. Vogel, S. Prisco, M. T. Patterson, J. Annis, R. T. Moon, L. M. Hartweck, J. B. Mendelson, M. Kim, N. Laixto Mancripe, T. Markowski, L. Higgins, C. Guerrero, B. Kremer, M. Blake, , K. Prins

This study investigates how ferroptosis contributes to pulmonary hypertension by integrating mitochondrial dysfunction and inflammation, showing that inhibiting ferroptosis reduces disease severity.

bioRxiv · Jan 19, 2023 · PreprintBiochemistry

Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules in Two Rodent Models of Pulmonary Arterial Hypertension

F. Kazmirczak, L. Hartweck, N. T. Vogel, J. B. Mendelson, J. Park, R. M. Raveendran, J. O-Uchi, B. S. Jhun, S. Prisco, K. Prins

This study shows intermittent fasting activates AMPK in rodent PAH models, improving RV lipid metabolism, mitochondrial function, and microtubule structure.

bioRxiv · Mar 7, 2022Biochemistry