BiochemistrybioRxiv
An auto-inhibited state of protein kinase G and implications for selective activation
R. Sharma, J. J. Kim, L. Qin…·C. W. Kim
This study presents crystal structures of PKG Iβ in auto-inhibited and activated states, revealing the mechanism of cGMP-mediated activation and isoform-specific regulation.
DOI 10.7554/elife.79530