Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens
M. Yao, J. Preall, J. Yeh, D. Pappin, P. Cifani, Y. Zhao, S. Shen, P. Moresco, B. He, H. Patel, A. Habowski, D. King, K. Raphael, A. Rishi, D. Sejpal, , D. Fearon
The paper identifies auto-antibodies secreted by plasma cells in PDAC against self-antigens, suggesting a link between chronic inflammation and autoimmunity.
bioRxiv · Mar 20, 2023 · PreprintCancer Biology