Author

J. Preall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 5

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Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:differential expression· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2

Frequent Co-Authors

D. Tuveson· 3 shared A. Rishi· 2 shared A. Deschenes· 1 shared A. Doshi· 1 shared A. Habowski· 1 shared A. Nemajerova· 1 shared A. P. Delgado· 1 shared A. Steep· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersCancer Biology

D. Tuveson

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5 papers

Recent·Most cited

ROR2 regulates cellular plasticity in pancreatic neoplasia and adenocarcinoma

S. Benitz, A. Steep, M. Nasser, J. Preall, U. M. Mahajan, H. McQuithey, I. Loveless, E. T. Davis, H.-J. Wen, D. W. Long, T. Metzler, S. Zwernik, M. Louw, D. Rempinski, D. Salas-Escabillas, , H. C. Crawford

This study identifies ROR2 as a regulator of cellular plasticity in pancreatic neoplasia, showing it promotes an aggressive PDAC phenotype and resistance to KRAS inhibitors.

bioRxiv · Dec 13, 2023Cancer Biology

Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens

M. Yao, J. Preall, J. Yeh, D. Pappin, P. Cifani, Y. Zhao, S. Shen, P. Moresco, B. He, H. Patel, A. Habowski, D. King, K. Raphael, A. Rishi, D. Sejpal, , D. Fearon

The paper identifies auto-antibodies secreted by plasma cells in PDAC against self-antigens, suggesting a link between chronic inflammation and autoimmunity.

bioRxiv · Mar 20, 2023 · PreprintCancer Biology

Single-cell transcriptome analysis reveals evolutionarily conserved features during the transition from normal breast stromal cells to cancer-associated fibroblasts

A. P. Delgado, A. Nemajerova, B. J. Nelson, M. Rao, J. Li, N. Marchenko, J. Preall, U. M. Moll, M. Egeblad, S. Powers

This study identifies conserved CAF subtypes in human and mouse breast tissues and reveals shared molecular mechanisms in their transition from normal stromal cells.

bioRxiv · May 5, 2022 · PreprintCancer Biology

SPDEF promotes the classical subtype of pancreatic ductal adenocarcinoma.

C. Tonelli, G. N. Yordanov, Y. Hao, A. Deschenes, O. Klingbeil, H.-C. Ting, E. Brosnan, A. Doshi, Y. Park, C. R. Vakoc, J. Preall, D. Tuveson

The paper identifies SPDEF as a key driver of the classical subtype of pancreatic ductal adenocarcinoma, showing its role in tumor progression and dependence on specific target genes.

bioRxiv · Mar 18, 2022 · PreprintCancer Biology

Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics

S. Bhatia, M. Kramer, S. Russo, P. Naik, G. Arun, K. Brophy, P. A. Andrews, C. Fan, C. M. Perou, J. Preall, T. Ha, D. Plenker, D. Tuveson, A. Rishi, J. E. Wilkinson, , D. L. Spector

This study develops and characterizes patient-derived TNBC organoids that recapitulate tumor properties and identify key signaling pathways involved in cancer progression.

bioRxiv · Aug 9, 2021Cancer Biology