K. S. Tan

This study evaluates a SARS-CoV-2 vaccine candidate that targets dendritic cells, showing durable systemic and mucosal immune responses against multiple variants.

This study shows chloroquine induces eryptosis in P. falciparum-infected red blood cells, releasing EVs with unique proteomic profiles that may activate immune pathways.

The paper identifies an additional signal in bacterial outer membrane proteins that enhances assembly efficiency and maintains membrane integrity through interaction with BamD.

This paper enhances kidney organoid maturation to produce functional proximal tubules, enabling better toxicity screening and infectious disease modeling.

The paper identifies enteroviral 3C proteases as the first cognate PAMP ligand for human NLRP1, showing they trigger inflammasome activation and airway inflammation.

This study identifies calcitriol, the active form of vitamin D, as a potent inhibitor of SARS-CoV-2, suggesting its potential as a prophylactic agent against COVID-19.

This paper shows that Plasmodium falciparum infects reticulocytes with higher affinity, alters drug sensitivity, and remodels host cells through transcriptomic changes.