Author

B. Reversade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Organism:zebrafish· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. E. T. Teo· 2 shared F. L. Zhong· 2 shared K. Robinson· 2 shared B. Al-Rawashdeh· 1 shared B. Kerouantan· 1 shared B. Merriman· 1 shared B. V. Au· 1 shared B. Wu· 1 shared

Activity by Year

2020-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

D. E. T. Teo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Opto-inflammasome in zebrafish: a tool to study cell and tissue responses to speck formation and cell death

E. Hasel de Carvalho, S. Dharmadhikari, K. Shkarina, J. R. Xiong, B. Reversade, P. Broz, M. Leptin

This paper introduces Opto-Asc, a light-controlled inflammasome tool in zebrafish to study speck formation and cell death, finding distinct morphological features of pyroptosis in periderm cells.

bioRxiv · Oct 19, 2022Immunology

Direct cleavage of human NLRP1 by enteroviral 3C protease triggers inflammasome activation in airway epithelium

K. Robinson, D. E. T. Teo, K. S. Tan, G. A. Toh, H. H. Ong, C. K. Lim, K. Lay, B. V. Au, T. S. Lew, J. J. H. Chu, V. T. K. Chow, D. Y. Wang, F. L. Zhong, B. Reversade

The paper identifies enteroviral 3C proteases as the first cognate PAMP ligand for human NLRP1, showing they trigger inflammasome activation and airway inflammation.

bioRxiv · Oct 14, 2020 · PreprintImmunology

INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly

L. G. Mascibroda, M. Shboul, N. D. Elrod, L. Colleaux, H. Hamamy, K.-L. Huang, N. J. Peart, M. K. Singh, H. Lee, B. Merriman, J. N. Jodoin, L. A. Lee, B. Al-Rawashdeh, O. Ababneh, M. El-Khateeb, , E. J. Wagner

This study identifies mutations in INTS13 causing a ciliopathy by disrupting Integrator complex assembly and ciliogenesis.

bioRxiv · Jul 20, 2020 · PreprintBiochemistry

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8

Q. Gong, K. Robinson, C. Xu, J. Zhang, Z. Z. Boo, D. E. T. Teo, Y. Zhang, J. S. Y. Lim, W. I. Goh, G. Wright, F. L. Zhong, B. Wu, B. Reversade

This study reveals the structural mechanisms by which NLRP1 and CARD8 assemble distinct inflammasome complexes through unique CARD domain interactions.

bioRxiv · Jun 17, 2020Immunology

BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

S. Zhang, C. Liang, C. Mary, B. Kerouantan, J. Francisco, N. S. Jagannathan, V. Olexiouk, J. H. Peh, C. Tang, G. Fidelito, S. Nama, R.-K. Cheng, C. L. Wee, L. C. Wang, P. D. Roggli, , L. Ho

The paper identifies BRAWNIN, a sORF-encoded peptide critical for vertebrate mitochondrial complex III assembly, showing its role in oxidative phosphorylation and metabolic function.

bioRxiv · Jan 31, 2020 · PreprintCell Biology