K. Schauer

Peripheral positioning of lysosomes supports melanoma aggressiveness

This study shows that lysosomal positioning in melanoma cells correlates with aggressiveness, promoting invasion and matrix degradation.

Membrane tension spatially organizes lysosomal exocytosis

This study shows that lysosomal exocytosis clusters spatially at the plasma membrane of RPE1 cells, driven by membrane tension patterns controlled by focal adhesions.

Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking

This study shows that persistent cell migration results from the interplay between protrusion dynamics and polarized trafficking, demonstrated through live-cell imaging and optogenetic experiments.

A comprehensive library of fluorescent constructs of SARS-CoV-2 proteins and their initial characterization in different cell types

The paper presents a library of fluorescent SARS-CoV-2 protein constructs and their initial characterization in human cell lines and yeast.

Transcription Factor EB regulates phosphatidylinositol-3-phosphate levels on endomembranes and alters lysosome positioning in the bladder cancer model

This study identifies TFEB's role in regulating PtdIns3P levels and lysosome positioning in bladder cancer, suggesting it as a potential biomarker and therapeutic target.

MYO1C facilitates arrival at the Golgi apparatus through stabilization of branched actin

This study identifies MYO1C as a myosin that stabilizes branched actin at the Golgi apparatus, facilitating transport carrier arrival and preventing Golgi fragmentation.