D. Kovacs

Surface tension-driven sorting of human perilipins on lipid droplets

The paper investigates how different human perilipins bind to lipid droplets by showing their varying affinities based on surface tension and lipid composition.

OSBP-mediated cholesterol transfer determines epithelial polarity and associated cargo secretion

This study shows OSBP-mediated cholesterol transfer is essential for epithelial polarity and cargo secretion, with OSBP inhibition disrupting apico-basal polarity and E-cadherin secretion.

COVID-19: A need for new rather than repurposed antiviral drugs.

This paper reviews 29 FDA-approved antiviral compounds for COVID-19 treatment, finds limited clinical efficacy of repurposed drugs, and highlights the need for novel antivirals.

A comprehensive library of fluorescent constructs of SARS-CoV-2 proteins and their initial characterization in different cell types

The paper presents a library of fluorescent SARS-CoV-2 protein constructs and their initial characterization in human cell lines and yeast.

Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor

The paper uses a fluorescent inhibitor to study OSBP lipid exchange and its effects on cellular processes.

Mast cells and γδ T cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization

This study shows that γδ T cells and mast cells are largely dispensable for adaptive immune responses after laser-mediated epicutaneous immunization, except for minor effects on IgG1 and effector T cells in mast cell-depleted mice.

Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties

This study shows that spontaneous interactions between proteins and RNA can form multi-layered condensates with distinct material properties and specific amino acid and RNA sequence dependencies.