Author

V. Sencio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Trottein· 4 shared A. Machelart· 2 shared P. Brodin· 2 shared A. Biela· 1 shared A. Danneels· 1 shared A. Guillon· 1 shared A. Mansart· 1 shared A. Mettouchi· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

F. Trottein

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections

F. Creusat, Y. Jouan, L. Gonzalez, E. Barsac, G. Ilango, R. Lemoine, D. Soulard, C. Boisseau, A. Guillon, Q. Lin, C. de Amat Herbozo, V. Sencio, N. Winter, F. Trottein, M. Si-Tahar, , C. Paget

The paper identifies PD-L1+ neutrophils in severe viral respiratory infections, showing they have regulatory functions and are generated in the bone marrow via IFN-γ.

bioRxiv · Nov 23, 2023Immunology

Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation

S. Solier, S. Muller, T. Caneque, A. Versini, L. Baron, P. Gestraud, N. Servant, L. Emam, A. Mansart, G. D. Pantos, V. Gandon, V. Sencio, C. Robin, F. Trottein, A.-L. Begue, , R. Rodriguez

The paper identifies a copper-signaling pathway involving CD44 and mitochondrial copper(II) that drives inflammation and cell plasticity, and shows a metformin-based drug reduces inflammation in infection models.

bioRxiv · Mar 29, 2022 · PreprintCell Biology

A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2

Y. Wu, N. Mahtal, L. Swistak, S. Sagadiev, M. Acharya, C. Demeret, S. Van der Werf, F. Guivel-Benhassine, O. Schwartz, S. Petracchini, A. Mettouchi, E. Paillares, L. Caramelle, P. Couvineau, R. Thai, , E. Lemichez

bioRxiv · Aug 13, 2021Microbiology

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

S. Belouzard, A. Machelart, V. Sencio, T. Vausselin, E. Hoffmann, N. Deboosere, Y. Rouille, L. Desmarets, K. Seron, A. Danneels, C. Robil, L. Belloy, C. Moreau, C. Piveteau, A. Biela, , J. Dubuisson

This paper identifies clofoctol as an antiviral against SARS-CoV-2, showing it inhibits viral replication and reduces lung pathology in mice.

bioRxiv · Jun 30, 2021 · PreprintMicrobiology