Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay
G. Juban, N. Sakakini, H. Chagraoui, Q. Cheng, K. Soady, B. Stoilova, C. Garnett, D. Waithe, J. Doondeea, B. Usukhbayar, E. Karkoulia, M. Alexiou, J. Strouboulis, E. Morrissey, I. Roberts, , P. Vyas
This study identifies stage-specific differentiation delays caused by GATA1s in megakaryocytes, leading to increased immature cells and altered gene expression.
bioRxiv · Oct 3, 2019Cell Biology