Author

K. Spirk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

A. Boersma· 1 shared A. Fenzl· 1 shared A. Kautzky-Willer· 1 shared A. Pichler· 1 shared A. T. Look· 1 shared B. Maurer· 1 shared C. Bock· 1 shared C. Schweicker· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Boersma

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

STAT5 Gain-of-Function Variants Promote Precursor T-Cell Receptor Activation to Drive T-Cell Acute Lymphoblastic Leukemia

T. Suske, H. Sorger, F. Ruge, N. Prutsch, M. W. Zimmerman, T. Eder, B. Maurer, C. Wagner, S. Schoenefeldt, K. Spirk, A. Pichler, T. Pemovska, C. Schweicker, D. Poeloeske, D. Jungherz, , R. Moriggl

This study identifies STAT5 gain-of-function mutations as drivers of T-ALL by promoting pre-TCR signaling and shows therapeutic targeting potential with STAT3/5 or ZAP70 inhibitors.

bioRxiv · Dec 21, 2022 · PreprintCancer Biology

Cold-mediated regulation of systemic retinol transport controls adipose tissue browning

A. Fenzl, O. C. Kulterer, K. Spirk, G. Mitulovic, R. Marculescu, M. Bilban, S. Baumgartner-Parzer, A. Kautzky-Willer, L. Kenner, J. Plutzky, L. Quadro, F. W. Kiefer

This study shows that cold exposure increases retinol and its transporter RBP in mice and humans, promoting adipose tissue browning and thermogenesis.

bioRxiv · Feb 7, 2020 · PreprintPhysiology