Cell BiologybioRxiv
UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
S. Ninagawa, M. Matsuo, D. Ying…·K. Mori
This study shows UGGT1 reglucosylation competes with EDEM-mediated degradation of misfolded glycoproteins, influencing ER protein quality control.
DOI 10.7554/elife.93117