BiophysicsbioRxivPreprint
Structural mechanism of leaflet-specific phospholipid modulation of a pentameric ligand-gated ion channel
J. T. Petroff, N. M. Dietzen, E. Santiago-McRae…·W. W. Cheng
The paper shows phosphatidylglycerol stabilizes the open state of ELIC by binding to a specific outer leaflet site, identified through structural and functional analyses.
DOI 10.1101/2022.06.07.494883