Author

M. Rau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:structural biology· 1

Frequent Co-Authors

P. Yuan· 2 shared Z. Deng· 2 shared B. Bothner· 1 shared B. Deng· 1 shared E. Antony· 1 shared E. Santiago-McRae· 1 shared G. Brannigan· 1 shared G. Maksaev· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

P. Yuan

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Author profile →

3 papers

Recent·Most cited

Homodecameric Rad52 promotes single-position Rad51 nucleation in homologous recombination

J. Deveryshetty, R. Chadda, J. Mattice, S. Karunakaran, M. Rau, K. Basore, N. Pokhrel, N. Englander, J. Fitzpatrick, B. Bothner, E. Antony

This study reveals that homodecameric Rad52 facilitates single-position Rad51 nucleation in homologous recombination through specific structural and interaction features.

bioRxiv · Feb 5, 2023 · PreprintBiochemistry

Structural mechanism of leaflet-specific phospholipid modulation of a pentameric ligand-gated ion channel

J. T. Petroff, N. M. Dietzen, E. Santiago-McRae, B. Deng, M. S. Washington, L. J. Chen, K. T. Moreland, Z. Deng, M. Rau, J. A. Fitzpatrick, P. Yuan, T. T. Joseph, J. Henin, G. Brannigan, W. W. Cheng

The paper shows phosphatidylglycerol stabilizes the open state of ELIC by binding to a specific outer leaflet site, identified through structural and functional analyses.

bioRxiv · Jun 7, 2022 · PreprintBiophysics

Cryo-EM structures of the ATP release channel pannexin 1

Z. Deng, Z. He, G. Maksaev, R. M. Bitter, M. Rau, J. A. J. Fitzpatrick, P. Yuan

This study presents cryo-EM structures of pannexin 1 from Xenopus tropicalis and Homo sapiens, revealing its heptameric architecture and molecular sieve mechanism for ATP release.

bioRxiv · Jan 5, 2020Biophysics