Author

K.-S. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:DNA methylation· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

B.-H. Jun· 3 shared H. Kim· 3 shared W.-j. Lee· 3 shared B.-S. Song· 2 shared C. H. Kim· 2 shared D.-S. Lee· 2 shared H. Lee· 2 shared J. K. Hur· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

B.-H. Jun

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Highly specific chimeric DNA-RNA guided genome editing with enhanced CRISPR-Cas12a system

H. Kim, W.-j. Lee, C. H. Kim, Y. Oh, L. W. Gwon, H. Lee, W. Song, J. K. Hur, K.-S. Lim, K. J. Jeong, K.-H. Nam, Y.-S. Won, Y. Lee, Y.-H. Kim, J.-W. Huh, , S. H. Lee

The paper enhances CRISPR-Cas12a system specificity and efficiency using a chimeric DNA-RNA guide, achieving 7.41 and 7.60 times improvements respectively.

bioRxiv · Sep 4, 2021Biochemistry

Expansion of the prime editing modality with Cas9 from Francisella novicida

Y. Oh, W.-j. Lee, H. Kim, L. W. Gwon, Y.-H. Kim, Y.-H. Park, C. H. Kim, K.-S. Lim, B.-S. Song, J.-W. Huh, S.-U. Kim, B.-H. Jun, C. Jung, S. Lee

This study expands prime editing by linking reverse transcriptase to FnCas9(H969A) nickase, enabling more precise and extended target gene modifications.

bioRxiv · May 25, 2021Bioengineering

Enhancement of Target Specificity of CRISPR-Cas12a by Using a Chimeric DNA-RNA Guide

H. Kim, W.-j. Lee, S.-H. Kang, J. K. Hur, H. Lee, W. Song, K.-S. Lim, Y.-H. Park, B.-S. Song, Y. B. Jin, B.-H. Jun, D.-S. Lee, S.-U. Kim, S. H. Lee

This study enhances CRISPR-Cas12a specificity by using a chimeric DNA-RNA guide, reducing off-target mutations in genome editing.

bioRxiv · Feb 4, 2020Biochemistry