BioengineeringbioRxiv
Expansion of the prime editing modality with Cas9 from Francisella novicida
Y. Oh, W.-j. Lee, H. Kim…·S. Lee
This study expands prime editing by linking reverse transcriptase to FnCas9(H969A) nickase, enabling more precise and extended target gene modifications.
DOI 10.1186/s13059-022-02644-8