Author

K.-W. Lo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

N. Mohana Kumaran· 3 shared S. F. Abdul Rahman· 2 shared A. Azlan· 1 shared A. S.-B. Khoo· 1 shared A. Thandoni· 1 shared A. Zloza· 1 shared B. G. Haffty· 1 shared B. S. X. Lian· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCancer Biology

N. Mohana Kumaran

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Author profile →

4 papers

Recent·Most cited

Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells.

S. F. Abdul Rahman, A. Azlan, K.-W. Lo, G. Azzam, N. Mohana Kumaran

This study identifies MCL-1 and BCL-XL as critical for NPC cell survival and shows that their dual inhibition enhances cytotoxicity in NPC cells.

bioRxiv · Jul 7, 2021Cancer Biology

Combinations of Indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of Nasopharyngeal carcinoma cell lines

G. Domnic, S. F. Abdul Rahman, N. J. Y. Chear, S. Ramanathan, K.-W. Lo, D. Singh, N. Mohana Kumaran

This study investigates the combination of indole-based alkaloids from kratom with cisplatin to inhibit nasopharyngeal carcinoma cell proliferation and migration.

bioRxiv · Dec 18, 2020 · PreprintCancer Biology

Acyclovir Improves the Efficacy of Chemoradiation in Nasopharyngeal Cancer Containing the Epstein Barr Virus Genome

A. Thandoni, A. Zloza, D. Schiff, M. Rao, K.-w. Lo, B. G. Haffty, S. Kim, S. R. Jhawar

This study shows that adding acyclovir to chemoradiation reduces viability of EBV-infected NPC cells by increasing TK and apoptosis markers.

bioRxiv · Oct 18, 2020 · PreprintCancer Biology

Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines

B. S. X. Lian, K.-W. Lo, A. S.-B. Khoo, N. Mohana Kumaran

This study evaluates Maritoclax and its combination with ABT-263 in NPC cell lines, showing single-agent and synergistic effects on cell proliferation and resistance in 3D spheroids.

bioRxiv · Nov 16, 2018Cancer Biology