ImmunologybioRxivPreprint
A class act: HDAC1-Malat1 regulates MDSC apoptosis and cell cycling to decrease suppression of T cells
Aaron G. Baugh, Yingtong Liu, Edgar Gonzalez…·Evanthia T. Roussos Torres
The paper shows HDAC1 inhibition in MDSCs increases Malat1, decreases pSTAT3, induces apoptosis and cell cycle arrest, and reduces T cell suppression.