Author
University of Oxford
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Britt Hanson, Nenad Svrzikapa, Ning Feng…·Thomas C. Roberts
The paper combines experimental and computational methods to model how uORFs regulate translation, identifying key features and interactions that influence their repressive activity.
Katarzyna Chwalenia, Vivi-Yun Feng, Nicole Hemmer…·Thomas C. Roberts
This paper introduces a novel DMD mouse model with non-uniform dystrophin expression and shows that partial dystrophin expression protects against muscle pathology.
Britt Hanson, Sofia Stenler, Nina Ahlskog…·Thomas C. Roberts
This study uses CRISPR to excise exon 23 in dKO mice, achieving partial dystrophin restoration but with limited efficacy and challenges in DNA repair.
Katarzyna Chwalenia, Jacopo Oieni, Joanna Zemła…·Thomas C. Roberts
This study shows that PPMO-mediated exon skipping in mdx mice restores uniform dystrophin expression and dose-dependently improves serum microRNA biomarkers and muscle biophysical properties.