NeuroscienceThe FASEB JournalPeer-reviewed
Increased activity of IRE1 improves the clinical presentation of EAE
Valerie C. Bracchi-Ricard, Kayla Nguyen, Daniela Ricci…·Yair Argon
This study shows that increased IRE1 activity in a mouse model of EAE reduces inflammation and improves motor function, suggesting context-dependent protective effects of ER stress.
4 citations