PathologyiSciencePeer-reviewed
Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems
Alessandra Tammaro, Eileen G. Daniels, Iman Man Hu…·Georges E. Janssens
This paper identifies a selective HDAC1/2 inhibitor, Cmpd60, that rejuvenates multiple organ systems in aged mice through transcriptional effects mimicking genetic longevity interventions.
21 citations