PhysiologybioRxiv
The Heart's Pacemaker Mimics Brain Cytoarchitecture and Function: Autonomic innervation, a peripheral glial cell web, and a novel S100B expressing interstitial cell type impart structural and functional complexity to the sinoatrial node
R. Bychkov, M. Juhaszova, M. Calvo-Rubio…·E. G. Lakatta
This study describes the 3D cytoarchitecture of the sinoatrial node, revealing autonomic innervation, peripheral glial cells, and a novel S100B-expressing interstitial cell type that contribute to its structural and functional complexity.
DOI 10.1016/j.jacep.2022.07.003