Cell BiologybioRxivPreprint
The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress
C. Anerillas, K. Mazan-Mamczarz, A. B. Herman…·M. Gorospe
This study identifies the YAP-TEAD pathway as a target for senolytic therapy, showing that inhibiting it induces apoptosis in senescent cells by increasing ER stress.
DOI 10.1101/2022.12.18.520921